A NOVEL AND SELECTIVE POLY (ADP-RIBOSE) POLYMERASE INHIBITOR AMELIORATES CHEMOTHERAPY-INDUCED PAINFUL NEUROPATHY.

A novel and selective poly (ADP-ribose) polymerase inhibitor ameliorates chemotherapy-induced painful neuropathy.

Chemotherapy-induced neuropathy is the principle dose limiting factor requiring discontinuation of many chemotherapeutic agents, including cisplatin and oxaliplatin.About 30 to 40% Fireplace Insert with Logs of patients receiving chemotherapy develop pain and sensory changes.Given that poly (ADP-ribose) polymerase (PARP) inhibition has been shown t

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Recent Fragmentation May Not Alter Genetic Patterns in Endangered Long-Lived Species: Evidence From Taxus cuspidata

Forestland fragmentation caused by overexploitation of forest resources can in principle reduce genetic diversity, limit gene flow and eventually lead to species developing strong genetic structure.However, the genetic consequences of recent anthropogenic fragmentation of tree species remain unclear.Taxus cuspidata, which has extremely small popula

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Energy Savings in Thermal Insulations for Sustainable Buildings

Energy use is second to staffing in building operating costs.Sustainable technology in the energy sector is based on utilizing renewable sources of energy such as solar, wind, glazing systems, insulation.Other areas of focus include heating, Chains ventilation and air conditioning; novel materials and construction methods; improved sensors and moni

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